教师基本信息
职称:教授
办公电话:021-31246550
电子邮箱:chnji@fudan.edu.cn
办公地点:mg4355娱乐线路检测官网C507室
个人简介
男,1970年出生,博士,教授。主要经历:1988-1992就读mg4355电子娱乐官网遗传及遗传工程系,1992获mg4355电子娱乐官网遗传学学士学位,1995获mg4355电子娱乐官网遗传学硕士学位,1998年获mg4355电子娱乐官网理学博士学位。1998至今于mg4355电子娱乐官网任讲师/副教授/教授,从事分子遗传学、结构生物学、基因工程等研究。
研究方向
利用分子遗传学、蛋白质晶体学、生物化学等手段,研究泛素化途径、核酸代谢途径、药物靶分子等重要蛋白的功能与结构之间的关系。
获奖情况
“教育部新世纪优秀人才计划”(Program for New Century Excellent Talents in University)和上海市青年科技启明星计划(Shanghai Rising-Star Program)资助,mg4355电子娱乐官网吴英蕃奖教金(Wu Yingfan Award)。
代表性论文和论著
1. Wang R, Li K, Zhou C, Xue J, Ji C*, Chen J*. Cdc20 mediates D-box-dependent degradation of Sp100. Biochemical and Biophysical Research Communications 415 (2011) 702–706
2. Ke Yu, Jing Zhang, Jiyuan Zhang, Chao Dou, Shaohua Gu, Yi Xie, Yumin Mao and Chaoneng Ji*.(2010) Methionine synthase A2756G polymorphism and cancer risk: a meta-analysis. European Journal of Human Genetics 18, 370–378.
3. Zheng M, Gu X, Zheng D, Yang Z, Li F, Zhao J, Xie Y, Ji C*, Mao Y. (2008).UBE1DC1, an ubiquitin-activating enzyme, activates two different ubiquitin-like proteins. J Cell Biochem. 104(6):2324-34.
4. Rong Jin,Linsen Dai,Jinbiao Zheng,Chaoneng Ji*.(2004). Purification and structural study of the β form of human cAMP-dependent protein kinase inhibitor. Eur.J.Biochem. 271:1768 –1773.
5. Jixi Li, Zhiyi Wei, Mei Zheng, Xing Gu, Yingfeng Deng, Rui Qiu,Fei Chen, Chaoneng Ji*, Weimin Gong*, Yi Xie and Yumin Mao. (2006) Crystal Structure of Human Guanosine Monophosphate Reductase 2 (GMPR2) in Complex with GMP. J. Mol. Biol. 355:980–988.