职称：教授
电话：02151630503
地址：mg4355电子娱乐官网江湾校区生命科学院
个人简介
1963年11月出生，女，mg4355电子娱乐官网特聘教授。
1991.9-1996.7，美国哥伦比亚大学，遗传学博士
1996-1997，法国国际癌症研究机构 博士后
1997-1998，美国匹兹堡大学 助理教授 (研究系列)
1998-2004，美国约翰·霍普金斯·布隆伯格公共卫生学院 助理教授
2004-2007，美国约翰·霍普金斯·布隆伯格公共卫生学院 副教授 (终身)
2007-2016，美国国家精神卫生研究所遗传流行病学研究组负责人
2016-今，美国国家精神卫生研究所统计基因组学和数据分析中心主任
2017-今，mg4355电子娱乐官网生命科学院特聘教授
研究方向
长期从事统计遗传学、精神病遗传学和计算生物学的研究
主要获奖及荣誉
2001年：约翰霍普金斯大学医学院“NIH Directors award”
2003年： 约翰霍普金斯大学公共卫生学院“The Louis I. and Thomas D. Dublin award”
2006年：约翰霍普金斯大学公共卫生学院 “The Helen Abbey Award for Advising, Mentoring and Teaching Recognition”
学术任职
2001年：美国人类遗传学会
2010年：国际遗传流行病学学会
2012年：国际精神病学遗传学大会
2007年：HUGO泛亚SNP数据库委员会
2016年：“World journal of psychiatry”编委
国际学术会议
1) UICC anti-cancer congress (1999), Japan
2) UICC Familial Cancer Project and International Oncology Conference (2001), China
3) Genetic Society of Hodgkin's Lymphoma (2001), German
4) Genomic Medicine (2011), China
5) Nature Conference: Genomic Analysis of Diseases (2012), China
6) International society of psychiatric genetics (2014), Denmark
7) International society of human genetics (2016), Japan
8）Biological Psychiatry Annual Conference, (2018), USA
撰写书籍
《Applied Computational Genomics》
代表性成果
(#并列一作，*通讯)
1. Bing-Jian, F., Huang, W., Shugart, Y.Y. #, et al.2002. Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4.;Nature genetics,;31(4), p.395.
2. Shugart, Y.Y. #, et al, 2006. Genomewide linkage scan for obsessive-compulsive disorder: evidence for susceptibility loci on chromosomes 3q, 7p, 1q, 15q, and 6q.;Molecular psychiatry,;11(8), p.763.
3. Qin H, et al, Nestadt G, Shugart, Y.Y.*, 2016. Whole genome association analysis of treatment response in obsessive-compulsive disorder.;Molecular psychiatry,;21(2), p.270.
4. Qin, H.D., Shugart, Y.Y. #, et al. and Zeng, Y.X., 2011. Comprehensive pathway-based association study of DNA repair gene variants and the risk of nasopharyngeal carcinoma.;Cancer research, pp.canres-0469.
5. Shugart, Y.Y. #, 1998. Anticipation in familial Hodgkin lymphoma.;American journal of human genetics,;63(1), p.270.
6. Qin, H.D., et al, Shugart, Y.Y.*, Jia WH*. 2016. Genomic characterization of esophageal squamous cell carcinoma reveals critical genes underlying tumorigenesis and poor prognosis.;The American Journal of Human Genetics,;98(4), pp.709-727.
7. Xu, Y., Yue, W., Shugart, Y.Y. #, et al., 2015. Exploring transcription factors-microRNAs Co-regulation networks in schizophrenia.;Schizophrenia bulletin,;42(4), pp.1037-1045.
8. Ritter, M.L., et al, Gerald Nestadt* and Shugart, Y.Y.* 2017. Genome Wide Association Study (GWAS) between Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD).;Frontiers in molecular neuroscience,;10.
9. Hong, S.E., Shugart, Y.Y., et al. and Walsh, C.A., 2000. Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations.;Nature genetics,;26(1), p.93.
10. Willour, V.L., Shugart, Y.Y., et al., 2004. Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder.;The American Journal of Human Genetics,;75(3), pp.508-513.
11. Ahn, K., An, S.S., Shugart, Y.Y. and Rapoport, J.L., 2016. Common polygenic variation and risk for childhood-onset schizophrenia.;Molecular psychiatry,;21(1), p.94.
12. Cao, H., Duan, J., Lin, D., Shugart, Y.Y., Calhoun, V. and Wang, Y.P., 2014. Sparse representation based biomarker selection for schizophrenia with integrated analysis of fMRI and SNPs.;Neuroimage,;102, pp.220-228.
13. Kiezun, A., Garimella, K., Do, R., Stitziel, N.O., Neale, B.M., McLaren, P.J., Gupta, N., Sklar, P., Sullivan, P.F., Moran, J.L. and Hultman, C.M., 2012. Exome sequencing and the genetic basis of complex traits.;Nature genetics,;44(6), pp.623-630.